Rfam 8.1 : Home (Janelia)

Rfam 8.1 (October 2007, 607 models)

Rfam is a collection of multiple sequence alignments and covariance models covering many common non-coding RNA families. The main use of Rfam is as a source of RNA multiple alignments with consensus secondary structure annotation in a consistent format. In conjunction with the Infernal software package, Rfam covariance models (CMs) can be used to search genomes or other DNA sequence databases for homologs to known structural RNA families.

Rfam makes use of a large amount of available RNA alignment data, especially published multiple sequence alignments, and repackages these data in a single searchable and sustainable resource. We have made every effort to credit individual sources on each family page (see the help page for a list). If you find any of the data presented here useful, please also be sure to credit the primary source.

Rfam is produced by the Rfam Consortium, a collaboration between researchers at the Wellcome Trust Sanger Institute near Cambridge, UK, the University of Manchester in Manchester, UK, and HHMI Janelia Farm near Washington, DC.

BROWSE RFAM	View Rfam annotation and alignments.
SEQUENCE SEARCH	Analyze a DNA query sequence to find Rfam family matches. (Links to Sanger Centre)
HELP	More information and help on Rfam.

FTP downloads from Rfam

Browse the Rfam FTP mirror site at Janelia Farm
Release notes for Rfam release 8.1.
Documentation of the Rfam flatfile formats.
Free redistribution information - Rfam is in the public domain.
Rfam.seed.gz - the seed alignments of the curated families (Stockholm format)
Rfam.full.gz - the full alignments of the curated families (Stockholm format)
Rfam.tar.gz - CMs for all families (Infernal format)
Rfam.fasta.gz - FASTA format file of EMBL 84 sequence covered by Rfam, filtered to <90% identity.